Hi Nate,
Tried each of those suggestions but no luck.
It only happens in animate mode and only when I'm deforming a mesh. When it does happen it locks up all the meshes in a project, not just the one I'm working on.
If I just reload the project it stays broken, I have to re-start Spine to get it to work again. I've attached the project but I suspect it's nothing to do with this project in particular (I've had it happen on other projects and the previous version of Spine)
It seems to be happening more frequently now I have more than one deformable mesh.
I'm using the PC pro version on Windows 10 Pro.
I was hoping it was a common problem with an easy answer : (